What do you consider "alot" of mileage for a car on the odometer reading?

100k miles is no longer considered "ready for the junkyard" unless the car has been seriously neglected or abused. I have a Ford van that just rolled over 200k miles and still burns no oil at all, factory engine and transmission are still going fine. If the car has been decently maintained I wouldn't really be concerned until over 200k miles, and I've seen Hondas and Toyotas from the 1990's that have over 300k on the factory engine and transmission and are still running fine.